TiO2 as an Efficient Catalytic Surface for Reduction of Carbonyl Compounds with NaBH4 under Solvent-free, Solid-gel and Microwave Irradiation

Davood Setamdideh*, Zahra Karimi and Fatemeh Rahimi

Department of Chemistry, Faculty of  Sciences, Mahabad Branch,  Islamic Azad University, Mahabad, 59135-443 (Iran).

Corresponding Author E-mail: davood.setamdideh@gmail.com

ABSTRACT:

Structurally different carbonyl compounds such as aldehydes, ketones, a,b-unsaturated enals and enones, a-diketones and acyloins were reduced efficiently by NaBH4/TiO2 system under solvent-free, solid-gel and microwave irradiation. The chemoselective reduction of aldehydes over ketones was achieved successfully by NaBH4/TiO2 system at solvent-free condition. In addition, regioselectivity and exclusive 1,2-reduction of conjugated carbonyl compounds to their corresponding allylic alcohols in high to excellent yields was accomplished successfully with this reducing system.

KEYWORDS:

NaBH4; TiO2; Solvent-free; Solid-gel; Microwave

Download this article as: 

Copy the following to cite this article: Setamdideh DKarimi Z, Rahimi F. TiO2 as an Efficient Catalytic Surface for Reduction of Carbonyl Compounds with NaBH4 under Solvent-free, Solid-gel and Microwave Irradiation. Orient J Chem 2011;27(4).

Copy the following to cite this URL: Setamdideh DKarimi Z, Rahimi F. TiO2 as an Efficient Catalytic Surface for Reduction of Carbonyl Compounds with NaBH4 under Solvent-free, Solid-gel and Microwave Irradiation. Orient J Chem 2011;27(4). Available from: http://www.orientjchem.org/?p=24234