ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Extractive Spectrophotometric Methods for the Determination of Darifenacin

Volume 26, Number 1

P.  Sai Praveen*, V. Jagathi, G. Devala Rao and G.Sudhakar Saibabu  

K.V.S.R. Siddhartha College of Pharmaceutical Sciences, Vijayawada - 520 010 (India).

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ABSTRACT:

Two simple and sensitive extractive spectrophotometric methods have been developed for the estimation of Darifenacin in pure and pharmaceutical dosage forms. These methods are based on the formation of ion-pair complexes of the drug with acidic dyes Solochrome black T (SBT: lmax 520 nm) and Methyl Orange (MO: lmax 420 nm). The absorbance of the chloroform extracts is measured against the corresponding reagent blanks. These methods have been statistically evaluated and found to be precise and accurate.

KEYWORDS:

Darifenacin; Spectrophotometric methods; pharmaceutical dosage forms

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Praveen P. S, Jagathi V, Rao G. D, Saibabu G. S. Extractive Spectrophotometric Methods for the Determination of Darifenacin. Orient J Chem 2010;26(1).

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Praveen P. S, Jagathi V, Rao G. D, Saibabu G. S. Extractive Spectrophotometric Methods for the Determination of Darifenacin. Orient J Chem 2010;26(1). Available from: http://www.orientjchem.org/?p=23572

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