Synthesis and physicochemical studies of copper complex of lansoprazole

Supriya Das¹, Suman Malik¹, Bharti Jain² and Seema Saini¹

¹Department of Chemistry, Sadhu Vaswani College, Bairagarh, Bhopal - 462 001 (India).

²Department of Chemistry, Sarojni Naidu Government Girls College, Bhopal - 462 003 (India).

ABSTRACT:

Copper (II) complex has been synthesized with Lansoprazole 2 [[[ methyl -4 (2,2,2 trifluroethoxy) 2-pyridinyl] methyl] sulfinyl] -1H-benzimidazole] (L) which is an antiulcerative drug. Complex has been characterized by elemental analysis, conductivity measurement, IR and NMR spectral studies. The molar conductance measurement of the complex in DMSO indicates that the complex is non ionic in nature. Spectral measurements showed that the ligand co-ordinates to metal ion through benzimidazole ring. The results show that ligand acts as bidentate and indicate square planar geometry of the metal complex.

KEYWORDS:

Copper complex; Lansoprazole; synthesis

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Copy the following to cite this article: Das S, Malik S, Jain B, Saini S. Synthesis and physicochemical studies of copper complex of lansoprazole. Orient J Chem 2009;25(4).

Copy the following to cite this URL: Das S, Malik S, Jain B, Saini S. Synthesis and physicochemical studies of copper complex of lansoprazole. Orient J Chem 2009;25(4). Available from: http://www.orientjchem.org/?p=22997