Novel synthesis and spectral characterization of some new substituted pyrazolones and isoxazolone

Alok K. Pareek*, P. E. Joseph and Daya S. Seth

Department of Chemistry,School of Chemical Sciences, St.John’s College, Agra - 282 002 (India).

ABSTRACT:

A Series of some new substituted pyrazolone derivatives containing different functional groups have been synthesized by the condensation reaction of 2-methoxy-5-methyl ethyl aceto hydrazone (1a) and different substituted phenyl malonamic acid hydrazides (2a-2k) in presence of glacial acetic acid as a catalyst, substituted isoxazolone (4a) have been synthesized by the condensation of 2-methoxy-5-methyl ethyl aceto hydrazone (1a) and hydroxylamine hydrochloride with sodium acetate. The constitution of the synthesized compounds are characterized by their elemental analysis, spectral studies like IR.

KEYWORDS:

Ethyl Acetohydrazone; Acid hydrazides; Glacial acetic acid; Condensation; Spectral data

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Copy the following to cite this article: Pareek A. K, Joseph P. E, Seth D. S. Novel synthesis and spectral characterization of some new substituted pyrazolones and isoxazolone. Orient J Chem 2009;25(4).

Copy the following to cite this URL: Pareek A. K, Joseph P. E, Seth D. S. Novel synthesis and spectral characterization of some new substituted pyrazolones and isoxazolone. Orient J Chem 2009;25(4). Available from: http://www.orientjchem.org/?p=22809