Synthesis, characterization and antibacterial screening of some novel biphenyl-4-carboxylic acid (4-benzylidene- 5-oxo-2-subsituted phenyl-4,5-dihydro-imidazol-1-yl)-amide

Vijay Trivedi¹* and Shailesh H. Shah²

¹Department of Chemistry, Arts, Commerce and Science College, Khambhat Dist.Anand, Gujarat (India).

²Department of Chemistry, Arts, Commerce and Science college Borsad, Dist: Anand, Gujarat (India).

ABSTRACT:

Imidazolinone derivatives of 4a-l have been prepared by the condensation of biphenyl-4-carboxylic acid hydrazide 2 with 5-oxazolone derivatives, which were prepared by Erlenmeyer condensation of benzoyl glycine with different aldehydes in the presence of sodium acetate and acetic anhydride. The compounds 3a-l was further reacted with biphenyl-4-carboxylic acid hydrazide 2 to give 4a-l in basic condition. The constitution of the products has been supported by IR, 1H-NMR, 13C-NMR Mass spectra and Elemental analysis data.

KEYWORDS:

Imidazolinone derivatives; synthesis; antibacterial screening

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Copy the following to cite this article: Trivedi V, Shah S. H. Synthesis, characterization and antibacterial screening of some novel biphenyl-4-carboxylic acid (4-benzylidene- 5-oxo-2-subsituted phenyl-4,5-dihydro-imidazol-1-yl)-amide. Orient J Chem 2009;25(4).

Copy the following to cite this URL: Trivedi V, Shah S. H. Synthesis, characterization and antibacterial screening of some novel biphenyl-4-carboxylic acid (4-benzylidene- 5-oxo-2-subsituted phenyl-4,5-dihydro-imidazol-1-yl)-amide. Orient J Chem 2009;25(4). Available from: http://www.orientjchem.org/?p=22678