ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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A Prenylated Isoflavone from Pouzolzia Indica : its in Vitro Antimicrobial Activity and Cytotoxin Evaluation

Volume 19, Number 1

Abu Sayeed1, M. A. Sattar1, M. Akteruzzaman2, Anwarul Islam3,

1Department of Applied Chemistry and Chemical Technology, Rajshahi University 2Department of Applied Chemistry and Chemical Technology, Islamic University, Kushtia 3Department of Pharmacy, Rajshahi University, Bangladesh

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ABSTRACT:

The chloroform extract of Pouzolzia indica (Urticaceae) has afforded a prenylated isoflavone, 5-methoxy-4-hydroxy-2, 2""-dimethylpyrano (3"",3"",7,8) isoflavone1, which is characterized by spectral (IR, MS, 1HMR and 13CNMR) studies. The compound exhibited potent antimicrobial and antifungal activities. The minimum inhibitory concentration (MIC) and cytotoxic activity (LC50 value) of the compound were found to be 32 μg ml-1 against Escherichia coli and 24.92 μg ml-1 against brine shrimp nauplii, respectively."

KEYWORDS:

Pouzolzia indica; isoflavonone; antimicrobial activity; cytotoxicity

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Sayeed A, Sattar M. A, Akteruzzaman M, Islam A. A Prenylated Isoflavone from Pouzolzia Indica : its in Vitro Antimicrobial Activity and Cytotoxin Evaluation. Orient J Chem 2003;19(1).

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Sayeed A, Sattar M. A, Akteruzzaman M, Islam A. A Prenylated Isoflavone from Pouzolzia Indica : its in Vitro Antimicrobial Activity and Cytotoxin Evaluation. Orient J Chem 2003;19(1). Available from: http://www.orientjchem.org/?p=17603

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